Overview

Title: Peptide purification by MCSGP - High yield and high purity with cost savings?
Date: Tuesday, April 17, 2018
Time: 10:00 AM Eastern Daylight Time / 16:00 Central European Time (convert to your local time)
Duration: ½ hour

Registration

Please follow this link to register.

Summary

MCSGP is a counter-current chromatography process that simultaneously achieves high yield and purity in difficult peptide purifications.

The increased yield of MCSGP …

• allows downscaling of the upstream chemical synthesis steps
• improves productivity of the downstream process leading to smaller columns required
• reduces solvent consumption
• eliminates the need for re-chromatography
• avoids generation of side-fractions to be stored and analyzed (reduction of analytical burden)

All above mentioned lead to massive cost savings compared to single column batch chromatography.

About the presenter

Thomas Müller-Späth, Ph.D., is the Chief Operating Officer of ChromaCon AG, a Swiss Life Science Tool company and a pioneer in continuous chromatography. He is also a senior scientist and lecturer in the research group of Prof. Massimo Morbidelli at ETH Zurich, Switzerland. Thomas has published numerous publications including 35 patents in the field of continuous downstream processing for peptides and proteins. Thomas is strongly involved in cooperation projects between academia and industry for the implementation of continuous processing from lab-scale to  GMP pilot & production scale.